Blog
Welcome to our blog! Explore educational content ranging from innovative treatments to insightful medical knowledge, curated by Dr. Rezaian, a specialist in Rheumatology and Internal Medicine.
Gender-Specific Insights into Axial Juvenile Spondyloarthritis: What the Data Reveals
Background/Purpose: The study explores the differences between males and females with axial juvenile spondyloarthritis (axJSpA), a type of juvenile inflammatory arthritis. The goal was to understand if there are distinct clinical and imaging features based on sex....
Exploring High-Dose Etanercept for Juvenile Arthritis: Does More Mean Better?
Background: Juvenile idiopathic arthritis (JIA) is a condition in children causing joint inflammation. Etanercept is a common medication for JIA, but the best dose for effectiveness is unclear. This study looks at whether increasing the dose of etanercept helps...
Ruxolitinib Delivers Life-Saving Results for Juvenile Arthritis Patients
Background: Systemic juvenile idiopathic arthritis (sJIA) is a severe form of arthritis in children that can lead to serious complications like macrophage activation syndrome (MAS) and lung disease. Even with current treatments like steroids and IL-1 inhibitors, some...
Long-Term Pain Relief: How a Plant-Based Diet Transforms Osteoarthritis Treatment
Background: The “Plants for Joints” (PFJ) program is a 16-week lifestyle intervention aimed at people with osteoarthritis (OA) of the hip or knee and metabolic syndrome. The program includes a whole-food, plant-based diet, physical activity, and stress management....
Breaking New Ground: Safe and Effective Gene Therapy for Knee Pain
Background: This study aimed to evaluate the safety and effectiveness of XT-150, a new gene therapy, for treating moderate to severe pain caused by osteoarthritis (OA) of the knee. XT-150 is designed to produce a special version of the anti-inflammatory protein...
Calcinosis Cutis: Unexpected Benefits Amidst Myopathic Challenges
Background: Idiopathic inflammatory myopathies (IIMs) are rare autoimmune diseases that primarily affect the muscles, causing inflammation. Calcinosis cutis, a condition where calcium deposits form in the skin, often accompanies connective tissue diseases, leading to...
New Hope for IgG4-Related Disease: Xeljanz Proves Effective
The article “Successful Treatment of Refractory IgG4-Related Disease with Tofacitinib: Experiences from 7 Patients” presents a study conducted at Peking University People’s Hospital. The study aimed to evaluate the effectiveness and safety of tofacitinib, a Janus...
Early Detection Game Changers: Identifying ILD in Autoimmune Diseases with Key Biomarkers
Study Background: This research focuses on finding reliable blood biomarkers to diagnose Interstitial Lung Disease (ILD) in patients with autoimmune diseases, specifically rheumatoid arthritis (RA) and systemic sclerosis (SSc). ILD is a serious complication in these...
Cutting-Edge Antibody Treatment Shows Efficacy in Knee Osteoarthritis Relief
The study titled “Efficacy, Safety, Pharmacokinetics and Immunogenicity of Repeated Dosing of GSK3858279 in Patients with Knee Osteoarthritis” aimed to evaluate a new treatment for knee osteoarthritis (OA) pain. This treatment, GSK3858279, is a human monoclonal...
Simponi and Tremfya: A Winning Combo for Ulcerative Colitis Remission
Background Ulcerative colitis is a chronic inflammatory condition affecting the colon. A recent study investigated the effectiveness of combining two drugs, Simponi, which blocks tumor necrosis factor-alpha, and Tremfya, which inhibits interleukin-23. This combination...
Meet The Author
M M Rezaian, MD
Rheumatology
Dr. Rezaian, who has dedicated over thirty years to the practice of Rheumatology, focuses on the utilization of biologic therapies for treating rheumatic diseases, the study of Spondyloarthropathy, and the innovative field of Telemedicine. He is connected with the WVU Berkeley Medical Center in Martinsburg, West Virginia.