by telrheum | Oct 6, 2024 | Osteoarthritis, Arthritis Supplements, Degenerative Arthritis, Orthopedic
This study explores the use of intra-articular (IA) liraglutide (LIRA), a glucagon-like peptide-1 (GLP-1) analog, for treating osteoarthritis (OA), a common age-related disease that causes chronic pain and restricts mobility. Current treatments, like corticosteroids...
by telrheum | Jun 16, 2024 | Degenerative Arthritis, Arthritis Supplements, Dietary Changes, Osteoarthritis
Background: The “Plants for Joints” (PFJ) program is a 16-week lifestyle intervention aimed at people with osteoarthritis (OA) of the hip or knee and metabolic syndrome. The program includes a whole-food, plant-based diet, physical activity, and stress management....
by telrheum | Jun 15, 2024 | Osteoarthritis, Antibody Therapy, Gene Therapy
Background: This study aimed to evaluate the safety and effectiveness of XT-150, a new gene therapy, for treating moderate to severe pain caused by osteoarthritis (OA) of the knee. XT-150 is designed to produce a special version of the anti-inflammatory protein...
by telrheum | May 26, 2024 | Osteoarthritis, Antibody Therapy, Degenerative Arthritis
The study titled “Efficacy, Safety, Pharmacokinetics and Immunogenicity of Repeated Dosing of GSK3858279 in Patients with Knee Osteoarthritis” aimed to evaluate a new treatment for knee osteoarthritis (OA) pain. This treatment, GSK3858279, is a human monoclonal...
by telrheum | Mar 24, 2024 | Osteoarthritis, Degenerative Arthritis
Voltage-gated sodium channels are crucial components of the nervous system, acting as gatekeepers that control the flow of sodium ions into nerve cells. This flow is essential for conducting electrical signals along neurons, allowing our bodies to perform functions...
by telrheum | Mar 23, 2024 | Osteoarthritis, Cell Therapy, Orthopedic
Cell therapies, particularly those using mesenchymal stem cells (MSCs), have been explored for their potential in treating osteoarthritis (OA), offering a more regenerative approach compared to traditional steroid injections. A systematic review and meta-analysis...