by telrheum | Sep 29, 2024 | Ankylosing Spondylitis, Biologic Therapy, Spondyloarthritis
The study explored the long-term safety and effectiveness of Bimekizumab (BKZ), a monoclonal antibody designed to block two proteins involved in inflammation, IL-17A and IL-17F. This dual inhibition helps control the excessive inflammation seen in ankylosing...
by telrheum | Sep 28, 2024 | Spondyloarthritis, Acute Phase Reactants, Ankylosing Spondylitis, C-reactive Protein, JAK Inhibitor, Tofacitinib
This article presents a post hoc analysis of how baseline (BL) C-Reactive Protein (CRP) levels affect the efficacy and safety of Tofacitinib, a medication used to treat Ankylosing Spondylitis (AS). Tofacitinib is a Janus kinase inhibitor, a type of drug that helps...
by telrheum | Sep 9, 2024 | Autoimmune Diseases, Juvenile Idiopathic Arthritis, Laboratory Testing, Psoriatic Arthritis, Spondyloarthritis, systemic juvenile idiopathic arthritis
The article “Potential Tear-Based Uveitis Biomarkers in Children with JIA: A Pilot Study” explores the possibility of using proteins found in tears to detect uveitis, an eye condition that can occur in children with juvenile idiopathic arthritis (JIA). Uveitis can...
by telrheum | Jun 25, 2024 | Psoriatic Arthritis, Interstitial Lung Disease, Rheumatoid Arthritis, Spondyloarthritis
Background and Purpose: Pulmonary issues are common yet often overlooked in people with rheumatic diseases like rheumatoid arthritis (RA), psoriatic arthritis (PsA), and peripheral spondyloarthritis (pSpA). These lung problems can lead to severe health consequences if...
by telrheum | Jun 21, 2024 | Biologic Therapy, Anti-TNF, Spondyloarthritis
This study investigated why some children with juvenile spondyloarthritis (JSpA) do not respond to TNF inhibitors (TNFi), a common treatment. Researchers analyzed data from patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA)...
by telrheum | Jun 19, 2024 | Psoriatic Arthritis, Spondyloarthritis
Background/Purpose: The study explores the differences between males and females with axial juvenile spondyloarthritis (axJSpA), a type of juvenile inflammatory arthritis. The goal was to understand if there are distinct clinical and imaging features based on sex....
