Blog
Welcome to our blog! Explore educational content ranging from innovative treatments to insightful medical knowledge, curated by Dr. Rezaian, a specialist in Rheumatology and Internal Medicine.
To Taper or Not: Unveiling the Impact of TNFi Withdrawal in RA Remission
The ARCTIC REWIND study explored the long-term effects of reducing and stopping tumor necrosis factor inhibitor (TNFi) treatment in patients with rheumatoid arthritis (RA) who were in sustained remission. The study involved randomly assigning patients who had been in...
Vagus Nerve Stimulation in RA: A Rigorous Trial Reveals No Therapeutic Benefit
The study explored the effectiveness and safety of auricular vagus nerve stimulation (VNS) in treating rheumatoid arthritis (RA). Earlier small or uncontrolled studies suggested VNS could reduce RA symptoms. In this larger, controlled trial, participants with active...
Unveiling the Brain’s Response to Arthritis Treatment: A Groundbreaking Functional MRI Study on Psoriatic Arthritis and TNFα Inhibition
The article discusses a study on how tumor necrosis factor-alpha (TNFα) inhibition, a treatment for psoriatic arthritis (PsA), affects pain processing in the brain, using functional magnetic resonance imaging (fMRI). The study included 6 PsA patients, some new to...
Breaking New Ground in Psoriasis Treatment: The Promise of Hemay005
Hemay005 is an experimental drug being tested for its ability to treat chronic inflammatory diseases like psoriasis by inhibiting a specific enzyme, PDE4, which plays a key role in the inflammation process. The drug aims to reduce the activity of T lymphocytes and...
AI Revolution in Spinal Health: Deep Learning Matches Radiologist Expertise in Detecting Axial SpA Inflammation
In this study, researchers focused on leveraging deep learning technology to enhance the diagnosis of axial spondyloarthritis (SpA), specifically by detecting active spinal inflammation through MRI scans. A total of 330 patients diagnosed with axial SpA were involved...
Revolutionizing Scleroderma Treatment: Breakthrough with CD19 CAR-T Cell Therapy
The article reports on a study where three patients with severe diffuse Systemic Sclerosis (SSc), a form of autoimmune disease, underwent a treatment involving CD19-targeting CAR-T cells. These cells are a type of therapy that modifies the patient’s T-cells to attack...
“Decades of Insight: Unveiling the Long-Term Journey of Primary Sjögren’s Syndrome”
The article “35 Years Follow-up of Primary Sjögren’s Disease: A Single Center Study” by Lorena Montano-Tapia and colleagues is a long-term study of patients with Primary Sjögren’s Syndrome (pSS), an autoimmune disease affecting exocrine glands. Conducted at the...
B Cells vs. ANCA: Unveiling the Best Path to Vasculitis Remission
The MAINTANCAVAS study, short for “Maintenance of ANCA Vasculitis Remission by Intermittent Rituximab Dosing,” was a clinical trial aimed at determining the best strategy to maintain remission in patients with ANCA vasculitis who have previously been...
Unlocking Relief: How Voltage-Gated Sodium Channels Hold the Key to Easing Osteoarthritis Pain
Voltage-gated sodium channels are crucial components of the nervous system, acting as gatekeepers that control the flow of sodium ions into nerve cells. This flow is essential for conducting electrical signals along neurons, allowing our bodies to perform functions...
Gut Reactions: Deciphering the Microbiome’s Influence on Autoimmune Disorders
The gut microbiome, an intricate community of microorganisms residing in our digestive tract, plays a pivotal role in shaping our health and disease states. Recent research has illuminated its significant influence on the immune system, particularly in the context of...
Meet The Author
M M Rezaian, MD
Rheumatology
Dr. Rezaian, who has dedicated over thirty years to the practice of Rheumatology, focuses on the utilization of biologic therapies for treating rheumatic diseases, the study of Spondyloarthropathy, and the innovative field of Telemedicine. He is connected with the WVU Berkeley Medical Center in Martinsburg, West Virginia.