by telrheum | Apr 21, 2024 | Biologic Therapy, Immunoglobulins, Infections
The study titled “Risk of Severe Infections Associated with Immunoglobulin Deficiency Under Rituximab Therapy in Immune Mediated Inflammatory Diseases” conducted by Claire Rempenault and colleagues, explored the connection between severe infections and...
by telrheum | Apr 7, 2024 | Biologic Therapy, Rheumatoid Arthritis
This article discusses a phase 3 clinical trial on telitacicept, a drug designed to treat rheumatoid arthritis (RA) in patients who have not responded well to methotrexate (MTX). Telitacicept is a recombinant fusion protein that targets and neutralizes two molecules,...
by telrheum | Apr 6, 2024 | Vasculitis, Biologic Therapy, Remove term: eosinophilic granulomatosis with polyangiitis eosinophilic granulomatosis with polyangiitis
The MANDARA study explored how effective and safe benralizumab is compared to mepolizumab for treating Eosinophilic Granulomatosis with Polyangiitis (EGPA), a condition that typically requires long-term treatment with oral glucocorticoids and immunosuppressants. This...
by telrheum | Apr 6, 2024 | Biologic Therapy, Rheumatoid Arthritis, tumour necrosis factor inhibitors (TNFis)
This study, conducted by researchers from Yonsei University College of Medicine in South Korea, investigated the risk of cardiovascular events like heart attacks or strokes in patients with ankylosing spondylitis (AS), a type of arthritis affecting the spine. They...
by telrheum | Apr 6, 2024 | Biologic Therapy, Sjögren’s Syndrome
Dazodalibep (DAZ) is a special type of protein used to treat Sjögren’s disease, which affects the immune system. In a study, patients with this disease took DAZ or a placebo (a treatment with no active drug) to see how effective and safe DAZ is. The study was...
by telrheum | Apr 6, 2024 | Biologic Therapy, Rheumatic Drugs, Rheumatoid Arthritis
The ARCTIC REWIND study explored the long-term effects of reducing and stopping tumor necrosis factor inhibitor (TNFi) treatment in patients with rheumatoid arthritis (RA) who were in sustained remission. The study involved randomly assigning patients who had been in...
